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DCPrime

Company Name

DCPrime BV

Institution

VU University Medical Center Amsterdam

The company

DCPrime BV is based on a technology platform around unique sustainable dendritic cell (DC) lines that can replace current patient-derived DC vaccines. DCPrime’s mission is to become “the new generation DC company” which develops off-the-shelf DC-based products.

Dendritic cell-based vaccines have been used in active immunotherapy for more than 10 years. Clinical results however have been inconclusive, because of the difficulty of product standardization. The reason for that is that such vaccines are prepared from patient’s own blood. DCPrime bypasses these problems by developing generic products that can be used in any patient. Unique patented culture processes for scalable manufacturing of functional DCs from sustainable cell lines have been developed, and these now make it possible to apply DCs as standardized off-the-shelf vaccines in the clinic. The DCPrime platform also has the advantage of offering numerous applications in additional R&D fields.