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Hep-Art Medical Devices

Company name

Hep-Art Medical Devices 

Institution

Academic Medical Center Amsterdam

The company

Hep-Art Medical Devices B.V. is a spin off company of the Academic Medical Center in Amsterdam. The company has developed a robust bio-artificial liver system, the AMC-BAL. The AMC-BAL has been developed to support acute liver failure (ALF) patients to liver recovery or to the moment of donor-liver availability. The AMC-BAL is an extracorporeal supportive device that treats the plasma of the patients and temporarily replaces liver functions. The core of the system is a bioreactor that is loaded with embedded liver cells (hepatocytes). When based on porcine liver cells, the system appeared safe during a first clinical phase 1 study with ALF patients.