ORCA Therapeutics

Company name

ORCA Therapeutics


VU University Medical Center Amsterdam

The company

ORCA Therapeutics B.V. is a privately-funded biopharmaceutical company designing and developing new oncolytic immunotherapies for treatment of cancer using Oncolytic Replication Competent Agents (ORCA). Their proprietary technologies allow them to engineer powerful oncolytic adenoviruses that selectively kill cancer cells and induce an antitumor immune response. ORCA’s lead compound ORCA-010 is being developed for patients with locally recurrent prostate cancer.

ORCA’s technology and IP portfolio originates from the groundbreaking research performed at the Department of Medical Oncology at the VU University Medical Center (VUmc) in Amsterdam, the Netherlands. ORCA is expanding its product portfolio through alliances with academic centres of excellence and industry partners. ORCA is based in the Netherlands: its corporate office is located in Nijmegen and R&D operations are in Amsterdam.