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Symposium TIFN - Maintaining Oral Health

Lessons learned from our microbiota

The community of microorganisms living in the oral cavity, known as the oral microbiota, has a significant impact on our oral health. Much like other groups of microbiomes residing on various parts of the body such as the skin, lungs and intestines, this collective community, as individualized as our fingerprints, has the ability to modulate our physiology and health, playing an often overlooked, but essential role in general well-being . Dysbiotic changes, in which this microbiota is thrown out of their balance, can thus lead to various oral and systemic diseases.

Luckily, the human microbiota displays, in composition and activity, a remarkable degree of resilience, despite frequent exposure to pathogenic, metabolic, and antimicrobial challenges. Thus a key question is how the human microbiota retains its compositional stability in symbiosis with its human host. Answering that question will help us with the development of novel early diagnostics, where we see stability derail before clinical damage becomes apparent. More importantly, it will allow us to develop preventive approaches to maintaining health, rather than repairing what has gone wrong, thus actively sustaining the symbiosis between the microbiota and our body.

This symposium will bring together scientists and clinicians from various fields and disciplines. The most recent findings on how different factors shape the microbe-host-ecosystem and how specific host-microbe interactions ensure stability of the human microbiota will be presented.

We will discuss how novel knowledge on the oral microbiota, as well as insights from microbiota on different parts of the human body, can be exploited for the benefit of our oral health.

Programme

Organizers and moderators: Prof. dr. Bart Keijser and Prof. dr. Wim Crielaard

09.00 - 09.30 am Registration

09:30 - 09:45 am Welcome and opening

09:40 - 10:15 am Lecture 1: ‘The oral microbiome and the maintenance of oral health’,
Prof. dr. Egija Zaura
Department of Preventive Dentistry, Academic Centre for Dentistry Amsterdam (ACTA)

10:15 - 10:50 am Lecture 2: ‘Using Faecal microbiota transplant (FMT) to dissect causality of intestinal microbiota in human metabolic disease’,
Prof. Dr. Max van Nieuwdorp
VU University Medical Center & Amsterdam Medical Center, The Netherlands

10:50 -11:20 am Coffee break

11:20 - 11:55 am Lecture 3: ‘Intestinal fungi in health and disease’,
Prof. dr. Wouter J de Jonge
Department of Gastroenterology, Academic Medical Center, Tytgat Institute for GI and Liver Disease

11:55 -12:30 pm Lecture 4: ‘What about your skin pets?’,
Dr. Jill de Wit
Department of Dermatology, Erasmus University Medical Center, Rotterdam, the Netherlands

12:30 - 13:30 pm Lunch break

13:30 - 14:05 pm Lecture 5: ‘Maturation of the respiratory tract microbiota in relation to respiratory health’,
Dr. Wouter Steenhuijsen Piters
Department of Paediatric Immunology and Infectious Diseases, Wilhelmina Children’s Hospital/University Medical Center Utrecht, The Netherlands Medical
Research Council/University of Edinburgh Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, United Kingdom


14:05 -14:40 pm Lecture 6: ‘Dynamics of the oral microbiome during experimental gingivitis’,
Dr. Andrei Prodan
Department of Preventive Dentistry, Academic Centre for Dentistry Amsterdam (ACTA)

14:40 - 15:10 pm Tea break

15:10 - 15:45 pm Lecture 7: ‘Immune - microbiome interactions; gatekeepers for oral health’,
Dr. Elena Nicu
Department of Periodontlogy, Academic Centre for Dentistry Amsterdam (ACTA)

15:45 - 16:30 pm Lecture 8: ‘A decade of studies on the human microbiome: challenges and promises’,
Dr. Elisabeth Bik
Science Editor at uBiome, Inc. in San Francisco, CA, USA

16:30 pm Drinks

Date: Thursday 11th of May 2017
Time: 9 am – 5 pm
Location: ACTA, Amsterdam
Entrance fee: € 125,-

  1. Registration
  2. Flyer event