Davide Iannuzzi, a physicist at VU Amsterdam, has been awarded a Proof of Concept grant by the European Research Council (ERC), for the DIADEPH project. He plans to use this €150,000 research grant to explore ways of commercializing a new, non-invasive gynaecological device that can improve population screening for cervical cancer by excluding cancer before taking a biopsy.
A ‘filter’ in the screening process
A team of researchers at VU Amsterdam, including Davide Iannuzzi (Professor of Biophotonics & Medical Imaging) and his former PhD student Luca Bartolini, is working on the DIADEPH project (also known as 2SIGNAL). They are developing an endoscope that can be used to image the cervix via a quick, cost effective, and non-invasive approach. This device obtains two known indicators of (pre)cancerous lesions: a subsurface 3D image of the cervix, and its stiffness. The new endoscope could function as a ‘filter’ in the screening process, helping to reduce the unnecessary biopsies by excluding (pre)cancerous lesions at an earlier stage. Moreover, if a biopsy is deemed necessary, this device may also be used to suggest the ideal sampling site.
In this video, Bartolini (the postdoctoral researcher at VU Amsterdam, co-inventor of the technique) summarizes the project as follows: “Our innovative medical device would improve the quality of life of millions of women that take part in cervical cancer screening programmes and reduce the physical, psychological and financial costs for them and society”.
From concept to commercially viable product
The physical examination made possible by the new endoscope may help gynaecologists to make more accurate diagnoses. Iannuzzi explains: “We have already developed a prototype for dermatological analysis. This research grant will enable us to analyse business opportunities and to identify each of the stakeholders needed to make the transition from a proof of concept to a commercially viable product. This will involve a collaborative effort by a team of physicists, engineers, medical doctors, and business developers.” In addition to the Proof of Concept grant, Iannuzzi has been awarded a Take-off grant by the Dutch Research Council (NWO – a science funding body), for the DIADEPH project.
In 2020, the ERC awarded a total of 166 Proof of Concept grants to scientists from 21 different countries. Four grants went to scientists at VU Amsterdam.
Teachers from the department of medical informatics of Amsterdam UMC have developed an online platform to gather and visualize structured curriculum information, called act-E. Education managers, teachers and students use this platform to gain insights regarding their curricula that could never be viewed as easily before. These insights help them to have an informed conversation […]News
Chronic kidney diseases are a severe and growing worldwide problem with a lack of effective treatments often leading to dialysis, transplantation, and high costs to health care systems. Now, a monoclonal antibody, named BION-1301 (anti-APRIL), is being developed to treat patients with IgA nephropathy. BION-1301 is a potential disease-modifying approach to prevent the formation of […]News
VU alumni International Business Administration Michael Musandu and Ugnius Rimsa founded Lalaland in 2019. The startup generates and hyper personalizes full human body models from head to toe by using AI. As a result, models are available in different ethnicities, sizes and ages, allowing customers to always recognize themselves in the clothing of their choice. […]News